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Medications for Parkinson's Disease Symptoms Found in the United States


In the United States, an experimental stem cell therapy called bemdaneprocel, developed by the company BlueRock, is reported to alleviate the symptoms of Parkinson's disease. This therapy targets early-stage Parkinson's disease symptoms.

Parkinson's disease disrupts brain function and is characterized by symptoms such as loss of muscle control, tremors, rigidity of movements, and cognitive impairment.

Researchers in the United States have announced the development of a promising method for treating Parkinson's disease using stem cells. Experts have transformed stem cells into dopamine-producing nerve cells, which were then implanted into the brains of individuals affected by Parkinson's disease. Additional medications to prevent immune system attacks were also used.

Bemdaneprocel (BRT-DA01) is an experimental therapy consisting of dopamine-producing neurons derived from pluripotent stem cells that are surgically implanted into the brains of people with Parkinson's disease. These cells have the potential to restore neural networks damaged by Parkinson's disease. Initial results showed that the cells multiplied and began producing dopamine.

Patients Improved

After a year of treatment, 7 out of 12 patients receiving high doses of the drug showed better control over their symptoms. The other 5 patients received a lower dose but also exhibited noticeable signs of disease reduction. The time to recurrence decreased by 0.75 hours per day. The treatment was well-tolerated and did not cause significant health problems.

American professors confirmed that the next phase of human trials will commence in the first half of 2024, and patient recruitment for the comparative group will start soon. The second and third stages of clinical trials will also take place in 2024.

Key Information:

Parkinson's disease is a brain disorder caused by damage to nerve cells, leading to a reduction in dopamine levels. The lack of this substance contributes to damage to neural connections, resulting in a gradual loss of motor function. Typical symptoms of Parkinson's disease include tremors, rigidity of movements, increased muscle tone, and speech disturbances.

According to the Parkinson’s Foundation, over 10 million people worldwide suffer from the disease. While there is no cure for Parkinson's disease, various methods exist to reduce the severity of its symptoms, including medication, non-pharmacological approaches, and surgical intervention.